GINI study summary

The German Infant Nutritional Intervention study (GINI)

von Berg A, et al

A summary of the GINI study 

The GINI study is a prospective, double-blind, randomised intervention trial of 2,252 infants at high risk of allergy. It was designed to assess the preventive effect of differently hydrolysed formulas compared with cows’ milk formula against allergy development. To date the infants were followed up at 1, 3, 6 and 10 years.

We’ve developed a summary of the GINI study in order to highlight the key outcomes from the trial publications that highlight the role of partially hydrolysed cows’ milk formula in the prevention of allergy in infants – it is available for download here:

 

The GINI Study

References

von Berg A et al. J Allergy Clin Immunol 2003; 111: 533–540.
von Berg A et al. J Allergy Clin Immunol 2007; 119: 718–725.
von Berg A et al. J Allergy Clin Immunol 2008; 121: 1442–1447.
von Berg A et al. Am J Clin Nutr 2011; 94(Suppl): 1803S–1897S.
von Berg A et al. J Allergy Clin Immunol 2013; 131 :1565–1573.

IMPORTANT NOTICE: Breast milk is best for babies and breastfeeding should continue for as long as possible. Good maternal nutrition is important for the preparation and maintenance of breastfeeding. Introducing partial bottle-feeding may have a negative effect on breastfeeding and reversing a decision not to breastfeed is difficult. Caregivers should always seek the advice of a doctor, midwife, health visitor, public health nurse, dietitian or pharmacist on the need for and proper method of use of infant milks and on all matters of infant feeding. Social and financial implications should be considered when selecting a method of infant feeding. Infant milk should always be prepared and used as directed. Inappropriate foods or feeding methods, or improper use of infant formula, may present a health hazard.