SMA PRO First Infant Milk | Formula Milk

Product description

SCIENCE INSPIRED BY NATURE

Appropriate growth

Clinically proven to achieve growth rate comparable with a breastfed baby.¹
Contains closer amino acid profile to that of breast milk, which is thought to help support appropriate growth^2,3

Immunity

Contains vitamin D which contributes to the normal functioning of baby’s immune system.⁴
Contains 2’FL* Human Milk Oligosaccharide (HMO): Research suggests that infants fed a formula supplemented with 2’FL* HMO had immune markers closer to breast-fed infants⁵

2’FL HMO is the most abundant oligosaccharide found in breast milk.⁶

To find out more about the role of HMOs in breast milk click here

The first 1000 days of a baby’s life have a life-long impact on many aspects of future health.

The growth pattern of a breastfed baby is associated with improved health outcomes.^{7, 8} Breastfed babies tend to grow more slowly than bottle-fed babies.⁹ Protein is one of the main drivers of growth, and the quantity and quality of protein in breast milk is ideal to support appropriate growth.

Halal Certified.

SMA^® PRO First Infant Milk is clinically proven to achieve a growth rate comparable to a breastfed baby, as defined by the World Health Organisation (WHO) growth standard¹

Uncover the WHO growth rates here

Chart 1. Green crosses represent average growth measurements in infants fed SMA^® PRO First Infant Milk compared with WHO growth standards. All measurements fall within ±0.5 standard deviation. The American Academy of Pediatrics recommends 3 g/day as a clinically relevant treatment difference for weight gain.¹⁰

SMA^® PRO First Infant Milk is supported by a meta-analysis demonstrating that weight-for-age, length-for-age, head circumference and BMI were all within 0.5 standard deviation of the WHO growth standard.¹

SMA^® PRO First Infant Milk has a closer amino acid profile (including insulinogenic amino acids) to that of breast milk, when compared with Aptamil First Infant Milk, as demonstrated in the graph below^{11, 12}

Discover the clinical evidence here

Percentage difference of insulinogenic amino acids compared with breast milk.³

Chart 2: Spider graph represents the insulinogenic amino acid percentage difference in each formula (SMA^® PRO First Infant Milk and Aptamil First Infant Milk), when compared with breast milk.

Available evidence from The Childhood Obesity Project Study, a large independent Randomised Controlled Trial (RCT), suggests that higher protein intakes increase plasma and tissue levels of insulin-releasing amino acids and of insulin and insulin-like growth factor 1 (IGF-1), and thereby increase weight gain and adipogenic activity.^{13, 14}

Growth rate comparable to a breastfed baby

SMA^® PRO First Infant Milk contains 1.24 g/ 100 ml (1.87 g/ 100 kcal) protein.

Based on the latest science, the level of protein in SMA^® PRO First Infant Milk has been lowered in resent years to help formula-fed infants achieve a slower growth rate comparable to that of a breastfed infant.¹ The growth patterns as seen in breastfed baby is associated with improved health outcomes.^8,9

To find out more about the science click here

Closer amino acid profile to breast milk^†

SMA^® PRO First Infant Milk has an essential amino acid profile similar to that of breast milk,2 and lower levels of insulinogenic amino acids compared with other first infant milks.¹

The amino acid profile of protein may have an important effect on the growth rate of infants.² Click here to find out more

^†powder only; liquids may vary

Immunity?

Vitamin D supports the normal functioning of the infants developing immune system⁴

2'FL* is a human milk oligosaccharide (HMO). HMOs are a key driver in establishing a healthy community of gut bacteria in newborn babies.⁶

Click here to learn more about HMOs and their role in infant nutrition.

References Show all Hide all

Alexander DD et al. Growth of infants consuming whey-predominant term infant formulas with a protein content of 1.8g/100kcal: a multi-center pooled analysis of individual participant data. Am J Clin Nutr 2016; 104: 1083–1092
Kirchberg FF, Harder U, Weber M, Grote V, Demmelmair H, Peissner W, et al. Dietary protein intake affects amino acid and acylcarnitine metabolism in infants aged 6 months. J Clin Endocrinol Metab. 2015;100(1):149-58.
Nestle data on file, 2018: Batch analysis of amino acid composition in SMA PRO First Infant Milk, Human Milk and Aptamil First Infant Milk, 2018
Scientific Opinion on the substantiation of a health claim related to Vitamin D and contribution to the normal function of the immune system pursuant to Article 14 of Regulation (EC) No. 1924/2006. EFSA Journal 2015; 13(5);4906
Goehring KC et al. Similar to Those Who Are Breastfed, Infants Fed a Formula Containing 2’- Fucosyllactose Have Lower Inflammatory Cytokines in a Randomized Controlled Trial J Nutr. 2016;146:2559–2566.
Vandenplas et al., Human Milk Oligosaccharides: 2-Fucosyllactose (2-FL) and Lacto-N-Neotetraose (LNnT) in Infant Formula. Nutrients 2018, 10, 1161
WHO Multicentre Growth reference Study group Acta Paediatr Suppl 2006; 450: 71H15.
Baird J et al Being big or growing fast: systematic review of size and growth in infancy and later obesity BMJ 2008; 331: 929.
Kramer MS et al Feeding effects on growth during infancy J Pediatr 2004; 145:500–505
American Academy of Pedatrics C.o.N. 1988 Clinical testing of infant formulas with respect to nutritional suitability for term infants. Prepared under FDA contract 223-86-2117.
SMA PRO First Infant Milk datacard.
Aptamil First Infant milk datacard. Available at https://www.nutricia.co.uk/hcp/pim-products/aptamil-first-infant-milk-with-pronutra-advance-powder.html (Accessed January 2021
Koletzko et al Lower Protein in infant formula is associated with lower weight up to 2y: a randomized clinical trial. Am J Clin Nutr 2009; 89: 1836–45.
Weber M et al Lower protein content in infant formula reduces BMI and obesity risk at school age: follow-up of a randomized trial Am J Clin Nutr 2014;99:1041–51

Data card

Download the datacard

References

Alexander DD et al. Growth of infants consuming whey-predominant term infant formulas with a protein content of 1.8g/100kcal: a multi-center pooled analysis of individual participant data. Am J Clin Nutr 2016; 104: 1083–109

Formats

SMA^® PRO First Infant Milk is available in a variety of formats for home and hospital use:

800 g powder

The scoop is provided under the lid. It can be stored in suspension inside the can.

400 g powder

Also available in a smaller 400 g size can.

Starter pack

6 x 70 ml plastic bottles and NUK^® orthodontic pre-sterilised teats.

No sterilising required. Disposable teats, screw directly onto the bottle.

(Available in UK only)

Multipack

6 x 200 ml Ready-to-Use cartons with a screwcap. Easy to open and pour and once open can be kept in the fridge for up to 24 hours.

Liquid milk
(1 L carton)

Ready to Use liquid milk available in a
1 litre resealable carton, which is easy to pour and can be kept in the fridge up to 48 hours after opening.

Liquid milk
(200 ml carton)

200 ml Ready to Use resealable carton, which is easy to pour and can be kept in the fridge for up to 24 hours.

70 ml bottle

For hospital use only.

NHS catalogue code (UK only): ABT082

United Drug Wholesale order code (Ireland only): 12443351

References Show all Hide all

Alexander DD et al. Growth of infants consuming whey-predominant term infant formulas with a protein content of 1.8g/100kcal: a multi-center pooled analysis of individual participant data. Am J Clin Nutr 2016; 104: 1083–1092

Comparison charts

SMA^® PRO First Infant Milk – developed to more closely match the composition of breast milk – in comparison with Aptamil, Cow & Gate and HiPP Organic first infant milks.

POWDER ONLY

	Breast milk	SMA^®PRO First Infant Milk²	Aptamil Profutura³	Aptamil First Infant Milk⁴	Cow & Gate First Infant Milk⁵	HiPP Organic First Infant Milk⁶
Non-nutritive biological factors (hormones, enzymes, growth factors etc
Protein levels per 100 ml	Varies	1.24 g*	1.3 g	1.3 g	1.3 g	1.25 g
Protein (whey:casein) ratio	60:40	70 : 30	60 : 40	50 : 50	60 : 40	60 : 40
Meta-analysis demonstrating growth comparable with a breastfed baby	n/a
Contains 2'FL the most abundant oligosaccharide in human milk⁷

References Show all Hide all

Alexander DD et al. Growth of infants consuming whey-predominant term infant formulas with a protein content of 1.8g/100kcal: a multi-center pooled analysis of individual participant data. Am J Clin Nutr 2016; 104: 1083–1092
SMA^® PRO First Infant Milk datacard. Click here to download datacard. (accessed February 2020).
Aptamil Profutura First Infant Milk datacard. Available at: https://eln.nutricia.co.uk/product-info/aptamil-profutura-first-infant-milk-2-2/ (accessed February 2020).
Aptamil First Infant Milk datacard. Available at: https://eln.nutricia.co.uk/product-info/aptamil-first-infant-milk-2/ (accessed February 2020).
Cow and Gate First Infant Milk datacard. Available at: https://eln.nutricia.co.uk/product-info/cow-gate-first-infant-milk-from-birth/ (accessed February 2020).
HiPP Organic First Infant Milk datacard. Available at: https://www.hipp4hcps.co.uk/fileadmin/media_hcp/pdf/HiPP_first_infant_milk_powder_data_card_170719.pdf (accessed February 2020).
Vandenplas et al., Human Milk Oligosaccharides: 2-Fucosyllactose (2-FL) and Lacto-N-Neotetraose (LNnT) in Infant Formula. Nutrients 2018, 10, 1161;

Preparation

How to open and prepare your baby's feed – powder (800 g and 400 g)

While this product is made under strict hygienic conditions, it is not sterile. Failure to follow instructions on preparation and storage may make your baby ill.

1. Pull the safety seal and open the lid. The scoop is provided under the lid. Lift the tab, pull on the foil seal, carefully and safely remove the seal and dispose of it.

2. Wash hands well. Wash and sterilise all utensils according to manufacturers’ instructions.

3. Boil 1 litre of fresh tap water. Allow boiled water to cool for no more than 30 minutes. Measure the required amount of water (see feeding guide) into a sterilised bottle, carefully – the water is hot. Do not use artificially softened or repeatedly boiled water.

4. Using only the scoop provided, add the correct number of scoops of powder (see feeding guide), levelling off each scoop with the back of a clean, dry knife. Store the scoop in suspension inside the can and replace lid.

5. Place the sterilised teat and cap on the bottle and shake well until powder is fully dissolved. Cool bottle under cold running water or in a bowl or jug of cold water until lukewarm, do not immerse the teat. Test temperature by shaking a few drops onto the inside of your wrist.

Preparing your baby's feed – liquid (70 ml Ready-to-Use)

Failure to follow instructions on preparation and storage may make your baby ill.

1. Wash hands well.

2. SMA^® PRO First Infant Milk 70 ml can be fed at room temperature. If required to heat, stand the bottle in warm water.

3. Shake bottle well and remove the cap and aluminium foil, unwrap SMA^® NUK^® orthodontic pre-sterilised teat and holding the ring, screw directly onto the bottle (as per on pack instructions).

4. If warmed, test temperature by shaking a few drops of milk onto the inside of your wrist – milk should be lukewarm.

Preparing your baby’s feed – liquid (1 litre & 200 ml Ready-to-Use)

Failure to follow instructions on preparation and storage may make your baby ill.

1. Wash hands well. Wash and sterilise all utensils according to manufacturers' instructions.

2. If carton is damaged in any way, do not use. Shake carton well and unscrew cap. Pour desired amount into a sterilised bottle and add sterilised teat and cap. Replace plastic cap on carton.

3. SMA^® PRO First Infant Milk can be fed at room temperature. If required to heat, stand filled bottle in warm water, do not immerse the teat.

4. Before feeding shake the bottle well. If warmed, test temperature by shaking a few drops onto the inside of your wrist – milk should be lukewarm.

Feeding guide

Feeding guide – powdered milk

Feeding guide birth – 12 months
Approx. age of baby	Approx. weight of baby		Preparation for single feeds			Feeds in 24 hours
	Approx. weight of baby			Cooled, freshly boiled water
	kg	lb	Level scoops	ml	fl. oz. (approx.)
Birth – 2 weeks	3.4	7½	3	90	3	6
2 – 4 weeks	3.7	8	4	120	4	6
4 – 8 weeks	4.2	9¼	4	120	4	6
2 months	5.3	11¾	5	150	5	5
3 months	6.1	13½	6	180	6	5
4 months	6.7	14¾	6	180	6	5
6 months	7.6	16¾	8	240	8	4
7 – 12 months	-	-	7	210	7	3

This table is a guide only; a baby may need more or less than the volumes stated. Caregivers should consult their healthcare professional if more advice is needed. Remember, a baby should be fed on demand. Mix 1 scoop of powder to 30 ml (approx. 1 fl. oz.) of water. Approx. 186 scoops per can (applicable to 800 g can only). 1 scoop = 4.3 g.

Feeding guide – liquid milk

Feeding guide birth – 12 months
Approx. age of baby	Approx. weight of baby		Size of feed		Feeds in 24 hours
Approx. age of baby	kg	lb	ml	fl. oz. (approx.)	Feeds in 24 hours
Birth – 2 weeks	3.4	7½	100	3½	6
2 – 4 weeks	3.7	8	130	4½	6
4 – 8 weeks	4.2	9¼	130	4½	6
2 months	5.3	11¾	170	6	5
3 months	6.1	13½	200	7	5
4 months	6.7	14¾	200	7	5
6 months	7.6	16¾	250	8½	4
7 – 12 months	-	-	200	7	3

References

Alexander DD et al. Growth of infants consuming whey-predominant term infant formulas with a protein content of 1.8g/100kcal: a multi-center pooled analysis of individual participant data. Am J Clin Nutr 2016; 104: 1083–1092

Important feeding information

SMA^® PRO First Infant Milk powder – 800 g and 400 g can

	Do not add extra powder or water to make the feeds stronger or weaker and do not press powder into scoop. Using too much or too little powder can make your baby ill.
	We recommend preparing each feed in individual bottles when required.
	For hygienic reasons, discard unfinished feed in the bottle as soon as possible.
	For older babies, made-up formulae can be added to food.
	Do not alter or add to formulae unless medically directed.
	Do not warm feeds in a microwave, hot spots may occur and cause scalding.
	Remember, cows' milk should not be used as a drink during the first year.

SMA^® PRO First Infant Milk Starter Pack – 70 ml bottle

	Special Safety Feature – Reject bottle if the foil under cap is missing or damaged prior to opening.
	Check best before date.
	After opening use immediately or store in the fridge (5 ºC or below) for up to 24 hours.
	For hygienic reasons, discard unfinished feed as soon as possible, and always within 1 hour.
	After use, discard bottle, teat and remaining contents. Bottles and teats are for single use only.
	Do not alter or add to formulae unless medically directed.
	Do not microwave, hot spots may occur and cause scalding.
	Remember, cows' milk should not be used as a drink during the first year.
	Do not freeze.

Important teat information for the child’s safety and health – WARNING!

	Teats are produced from natural rubber latex which may cause allergic reactions.
	Disposable teat (for single use only).
	This NUK^® disposable orthodontic pre-sterilised teat is a size 1 teat (appropriate for babies from 0–6 months) with a feed hole suitable for infant milk. Use with SMA^® PRO First Infant Milk 70 ml bottles.
	Give your baby’s feed only in the quantities and concentrations recommended by the manufacturer.
	Always check the food temperature before feeding.
	Always use this product with adult supervision.
	Continuous and prolonged sucking of fluids may cause tooth decay.
	Never use feeding teats as a soother.
	Teat expiry date: See individual teat.
	Do not dip in medicine.
	The NUK^® disposable orthodontic pre-sterilised teat (manufactured for SMA^® Nutrition) conforms to the requirements of EN14350.

SMA^® PRO First Infant Milk liquid – 1 litre Tetra-Pak^®

	Check best before date.
	Once open, reseal carton and store only in the fridge (5 ºC or below). Consume within 48 hours.
	For hygienic reasons, discard unfinished feed in the bottle as soon as possible, and always within 1 hour.
	For older babies, ready to use formulae can be added to food.
	Do not alter or add to formulae unless medically directed.
	Do not warm feeds in a microwave, hot spots may occur and cause scalding.
	Remember, cows' milk should not be used as a drink during the first year.
	Do not freeze.

SMA^®PRO First Infant Milk liquid – 200 ml Tetra-Pak

	Check best before date.
	Once open, reseal carton and store only in the fridge (5 ºC or below). Consume within 24 hours.
	For hygienic reasons, discard unfinished feed in the bottle as soon as possible, and always within 1 hour.
	For older babies, ready to use formulae can be added to food.
	Do not alter or add to formulae unless medically directed.
	Do not warm feeds in a microwave, hot spots may occur and cause scalding.
	Remember, cows' milk should not be used as a drink during the first year.
	Do not freeze.

*2'FL: structurally identical human milk oligosaccharides, not sourced from breast milk

Important Notice:

The World Health Organisation (WHO) has recommended that pregnant women and new mothers be informed on the benefits and superiority of breastfeeding – in particular the fact that it provides the best nutrition and protection from illness for babies. Mothers should be given guidance on the preparation for, and maintenance of, lactation, with special emphasis on the importance of a well-balanced diet both during pregnancy and after delivery. Unnecessary introduction of partial bottle-feeding or other foods and drinks should be discouraged since it will have a negative effect on breastfeeding. Similarly, mothers should be warned of the difficulty of reversing a decision not to breastfeed. Before advising a mother to use an infant formula, she should be advised of the social and financial implications of her decision: for example, if a baby is exclusively bottle-fed, more than one can (400 g) per week will be needed, so the family circumstances and costs should be kept in mind. Mothers should be reminded that breast milk is not only the best, but also the most economical food for babies. If a decision to use an infant formula is taken, it is important to give instructions on correct preparation methods, emphasising that unboiled water, unsterilised bottles or incorrect dilution can all lead to illness.

SMA® PRO First Infant Milk

SMA^® PRO First Infant Milk